The rapidly evolving field of protein design is revealing solutions to some of the world’s greatest problems, whether it's blocking a virus, breaking down a pollutant or creating brand-new materials. In conversation with TED’s Whitney Pennington Rodgers, biochemist David Baker explores his team’s Nobel Prize-winning work using AI to design new proteins with functions never before seen in nature — achieving breakthroughs that have fundamentally changed the future of science. (This conversation was part of an exclusive TED Membership event. TED Membership is the best way to support and engage with the big ideas you love from TED. To learn more, visit ted.com/membership.) (Recorded at TED Membership on June 11, 2025) Join us in person at a TED conference: https://tedtalks.social/events Become a TED Member to support our mission: https://ted.com/membership Subscribe to a TED newsletter: https://ted.com/newsletters Follow TED! X: https://www.twitter.com/TEDTalks Instagram: https://www.instagram.com/ted Facebook: https://facebook.com/TED LinkedIn: https://www.linkedin.com/company/ted-conferences TikTok: https://www.tiktok.com/@tedtoks The TED Talks channel features talks, performances and original series from the world's leading thinkers and doers. Subscribe to our channel for videos on Technology, Entertainment and Design — plus science, business, global issues, the arts and more. Visit https://TED.com to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more. Watch more: https://go.ted.com/davidbaker25 https://youtu.be/k-9sQXhHHmk TED's videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy: https://www.ted.com/about/our-organization/our-policies-terms/ted-talks-usage-policy. For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at https://media-requests.ted.com #TED #TEDTalks #Biology