- Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer’s, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketogenesis. He’s held faculty positions at the University of Brussels, the NIH and the Picower Institute for Medical Research. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/eric-verdin?utm_source=youtube&utm_medium=youtube&utm_campaign=verdin_interview Dr. Eric Verdin on Twitter: http://twitter.com/ericverdin Dr. Eric Verdin's Lab - Buck Institute for Research on Aging: http://verdin.buckinstitute.org/ PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=verdin_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/040-dr-eric-verdin-on-ketogenic-diet-longevity-beta/id818198322?i=1000532219463 Spotify: https://open.spotify.com/episode/2g9srUjp3ZqRGPk0QSJO6O Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi Chapters: 00:00:00 - Prolonging lifespan 00:01:08 - Aging research 00:03:30 - Insulin and aging 00:09:05 - HDAC Inhibition from Ketones 00:20:31 - Protein activates mTOR & IGF-1 00:23:05 - PPAR-alpha activation 00:28:11 - Artificial intelligence predicts age 00:32:05 - NAD+ effect on aging 00:45:16 - Ketogenic diet safety 00:48:41 - Intermittent fasting SCIENCE OF HEALTHSPAN EMAIL NEWSLETTER: Receive emailed episode notifications and regular updates on the emerging science of healthspan. https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=verdin_interview SUPPORT THE CHANNEL: Many of the magnificent resources associated with the FoundMyFitness channel exist directly as a result of our premium membership. As a premium member, listeners get access to our exclusive podcast The Aliquot, monthly Q&As, a special summary of scientific research every other week called the Science Digest, and more. Sign up to become a premium member and nurture the existence of all of the otherwise free resources provided by FoundMyFitness at https://www.foundmyfitness.com/crowdsponsor?utm_source=youtube&utm_medium=youtube&utm_campaign=verdin_interview Thank you for watching! SOCIALS: https://twitter.com/foundmyfitness https://facebook.com/foundmyfitness https://instagram.com/foundmyfitness PODCAST: Apple Podcasts: https://podcasts.apple.com/us/podcast/foundmyfitness/id818198322 Spotify: https://open.spotify.com/show/5QjpaU0o1Q2MkVZwwG3y7d 🍗 #keto #nutrition #aging #fasting ✨