Journalist Derek Thompson joins Scott Galloway to examine why Americans feel increasingly unhappy — even as many measures of health, safety, and quality of life improve. They discuss how media incentives and negativity bias distort our perception of reality, why outrage dominates online discourse, and how social comparison and screen-based life erode well-being. Derek also explores the impact of AI on inequality, the promise and limits of GLP-1 drugs, and why progress in technology and health hasn’t translated into greater happiness or connection. Timestamps 00:00 - In This Episode 00:49 - Can you share a bit about your recent paternity leave? 02:04 - How do you feel about paternity leave? 07:08 - Could cash transfers be an alternative to paternity leave? 11:45 - Which of the themes and trends you're watching for 2026 feel most relevant right now? 16:20 - Are algorithms and constant comparison keeping us unhappy? 20:32 - Are China and Russia playing a part in dividing us? 23:36 - Ad Break 26:47 - What are your thoughts on GLP-1s? 31:49 - Are GLP-1s the best way to reduce healthcare costs? 39:31 - What is your approach to substances like alcohol and GLP-1s? 44:38 - Should young people drink more? 48:56 - Ad Break 51:13 - At what levels is AI creating inequality? 53:12 - How did you build and manage your media career flywheel? 1:00:23 - What are your thoughts on Substack? 1:04:09 - How do you price your content? 1:04:48 - Do you have any regrets about the prices you chose? Please support this channel by subscribing here: https://links.profgmedia.com/youtube-... Want more Prof G? Check out everything we're up to at https://links.profgmedia.com/home #ProfGMedia #ProfGConversations #ProfG #ScottGalloway #Politics #Economy #Tech #Culture #AI #Business #Leadership #Strategy #Innovation #Podcast #Interview #Insights #Culture