Full title: #49 – Matthew Walker, Ph.D., on sleep – Part III of III: The penetrating effects of poor sleep from metabolism to performance to genetics, and the impact of caffeine, alcohol, THC, and CBD on sleep Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 4/15/19 In the final part of this 3 part series, Matthew Walker, professor of neuroscience at UC Berkeley and expert on sleep, discusses the omnipresent effects of insufficient sleep on everything from metabolism, appetite, athletic performance, decision-making, productivity, leadership, mental health, genetics, memory, and more. We also discuss the impact of caffeine and alcohol on sleep quality, the efficacy of sleep aids such as THC and CBD, and much more. We discuss: -Sleep and insulin resistance [6:15]; -Epigenetic changes with insufficient sleep, and the reversibility of lost sleep [18:00]; -Sleep’s impact on exercise performance, appetite, and food choices [28:15]; -Decision making, workplace production, leadership qualities, physical attractiveness, and more [43:15]; -The broken water pipe analogy [49:30]; -The negative effect of caffeine, alcohol, and high carb meals on sleep quality [53:30]; -The efficacy of THC and CBD as sleep aids [1:05:30]; -Sleep and mental health: A two-way street [1:16:45]; -How sleep impacts memory, and Matthew’s current and upcoming projects [1:24:00]; -Sleep’s impact on athletes: Looking at Formula One drivers [1:32:45]; -Translating the science to clinical application [1:57:00]; and -More. Show notes page: https://peterattiamd.com/matthewwalker3/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipidology, pharmacology, and four-system endocrinology to increase lifespan (delaying the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Play: http://bit.ly/TheDriveGooglePlay