Robert Krikorian is Professor in the Department of Psychiatry & Behavioral Neuroscience and Director of the Cognitive Aging Program at the University of Cincinnati Academic Health Center. His clinical and research interests include changes in cognition with aging, the influence of health conditions on memory decline and risk for Alzheimer’s disease, and approaches to delay progression of neurodegeneration. His current research involves investigations of the effects of dietary manipulation and non-pharmaceutical interventions, such as berry fruit supplementation and ketogenic diets, on neurocognitive function in middle-aged and older adults. Learn about: 1:06 - Dr. Krikorian's unique scientific career and how he arrived at his current interest 8:04 - Dr. Krikorian's research on ketogenic diets and mild cognitive impairment (pre-dementia) 14:47 - The relationship Dr. Krikorian has found between insulin and cognitive function 17:18 - Improvements in other neurochemicals after patients adopted a low carb diet 19:55 - Autophagy and ketone metabolism 22:16 - Why reducing carbs (and protein) is more important for ketone generation than eating fat 25:15 - The effect of ketones on biomarkers and other features of Alzheimer's disease 27:45 - The diabetic brain / "Type 3 diabetes" theory of Alzheimer's disease 31:40 - Another housecleaning enzyme - Insulin Degrading Enzyme - and its relationship to Alzheimer's 32:30 - How young people can optimize their brains 37:09 - Dr. Krikorian's thoughts on MCT oil and exogenous ketones 41:30 - Why Dr. Krikorian became interested in berries and anthocyanin as a cognitive-enhancing food 50:12 - Learn Dr. Krikorian's own diet and supplement regimen (he's kind of a badass) ▶ JOIN MY MAILING LIST: http://maxlugavere.com ▶ SUBSCRIBE TO MY CHANNEL: http://bit.ly/maxsyoutubechannel Find me: More Videos: http://youtube.com/maxlugavere Facebook: http://facebook.com/maxlugavere Instagram: http://instagram.com/maxlugavere Twitter: http://twitter.com/maxlugavere