Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 12/10/18 In this episode, Siddhartha Mukherjee, oncologist, researcher, and author of the Pulitzer Prize-winning book, The Emperor of All Maladies: A Biography of Cancer, discusses his writing process, his thoughts about medicine, cancer, immunotherapy, and his recent collaboration on a study combining a ketogenic diet with a drug in mice that provided remarkable and encouraging results. We discuss: -Sid’s background [5:00]; -How Sid and Peter met [6:00]; -Sid’s Pulitzer Prize-winning book: The Emperor of All Maladies [8:00]; -Sid’s writing process: the tenets of writing [12:30]; -Our struggle to find preventable, human, chemical carcinogens of substantial impact [23:30]; -The three laws of medicine — Law #1: A strong intuition is much more powerful than a weak test [26:30]; -Law #2 of medicine: “Normals” teach us rules; “outliers” teach us laws [32:00]; -Law #3 of medicine: For every perfect medical experiment, there is a perfect human bias [35:00]; -The excitement around immunotherapy [38:15]; -The story of Gleevec [46:00]; -How does the body’s metabolic state affect cancer? [49:30]; -Can a nutritional state be exploited and/or a drug sensitivity be exploited through a nutritional intervention? [52:00]; -How does Sid balance his family, writing, research, laboratory, and patients? [1:00:30]; and -More. Show notes page: https://peterattiamd.com/sidmukherjee/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipidology, pharmacology, and four-system endocrinology to increase lifespan (delaying the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Play: http://bit.ly/TheDriveGooglePlay