When it comes to “bad” cholesterol, most cardiologists say lower is better. But what’s the best way to get that number down? Can diet and exercise alone do the job? Cardiologists Kiran Musunuru and Neha Pagidipati join Host Ira Flatow for a look at the latest in cholesterol-lowering treatments (https://www.sciencefriday.com/segments/new-cholesterol-treatment-crispr/?utm_source=wnyc&utm_medium=podcast&utm_campaign=scifri) , including CRISPR technology that could turn off cholesterol-making genes for life. How does it work, and is it safe? Guests: Dr. Kiran Musunuru is the scientific director of the Center for Inherited Cardiovascular Disease at the Perelman School of Medicine at the University of Pennsylvania. Dr. Neha Pagidipati is the director of the Cardiometabolic Prevention Clinic at the Duke University School of Medicine in Durham, NC. Transcripts for each episode are available within 1-3 days at sciencefriday.com. (https://www.sciencefriday.com/segments/new-cholesterol-treatment-crispr/?utm_source=wnyc&utm_medium=podcast&utm_campaign=scifri)   Subscribe to this podcast. (https://pod.link/73329284) Plus, to stay updated on all things science, sign up for Science Friday's newsletters (https://www.sciencefriday.com/newsletters/?utm_source=wnyc&utm_medium=podcast&utm_campaign=scifri) .