This talk was recorded live at the All-In Summit 2023 at Royce Hall on UCLA's campus in Los Angeles. (0:00) Besties welcome Dr. Nicole Paulk to All-In Summit ‘23! (0:59) An introduction to Gene Therapy (2:18) Three eras of modern medicine (4:49) Living medicines (6:35) Congenital blindness and other rare diseases (9:37) Gene therapy applications for broad use, including cancer (12:00) Immunosurveillance and immunotherapy (14:44) Brain cancer test (16:34) DEC2 mutation to reduce the need for sleep (17:45) Gene therapy for people living on Mars (18:40) Bestie Q&A: FDA hurdles and aging as a disease state (21:16) Biotech’s valley of death (23:52) Night vision and other human enhancements (26:32) Fundraising Follow Nicole: https://twitter.com/Nicole_Paulk Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Relevant links: https://twitter.com/SirenBio https://sirenbiotechnology.com/