In an era of popular weight loss drugs, including GLP-1 agonists like Ozempic (semaglutide), Victoza (liraglutide), Wegovy, and Saxenda, many people are looking for safer, natural alternatives. https://www.drugs.com/ozempic.html Calocurb (use code BEN10 to save 10%) is a patented natural plant-based supplement clinically proven to reduce hunger by 30%, cravings by 40%, and calorie intake by an average of 18% — in just an hour. It does this by stimulating the body's own "feel full" hunger hormones cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), and peptide YY (PYY). https://bengreenfieldlife.com/calocurb In this episode, Dr. Edward Walker, a scientist and lecturer who helped develop Calocurb, will introduce you to the concept of the "bitter break" and the powerful plant extract, Amarasate, which has shown remarkable results in stimulating anti-appetite hormones when delivered to the small intestine. You'll also get to explore the science behind how this extract works, its impact on glucose and insulin levels, and much more! https://www.linkedin.com/in/edward-walker-30487b17/?originalSubdomain=nz Dr. Walker completed his Ph.D. on the antioxidant effects of berry fruits at the University of Auckland and has continued to research how dietary plant compounds can improve health and wellness. He works at The New Zealand Institute for Plant and Food Research, undertaking commercially focused research of nutraceutical products for human health applications, with a focus on clinical validation of lab-based results. He is also a guest lecturer at the University of Auckland on the topic of nutraceuticals and functional foods. https://www.plantandfood.com/en-nz/ Over the last 13 years, Dr. Walker's primary research focus has been the investigation of plant-based appetite suppressants that may reduce hunger and support healthy food choices. This work led to the development of Amarasate, a novel New Zealand hops-based appetite suppressant that shares an overlapping mode of action with a new class of effective GLP-1-based anti-obesity drugs. He is passionate about plant-based nutraceuticals and believes that with the appropriate scientific research, they have the potential to improve health and wellness, and even prevent or delay the development of chronic disease. Whether you're interested in nutrition, weight management, or cutting-edge health science, this episode is packed with insights you won't want to miss. Tune in and discover how you can take control of your cravings and support your journey to better health! What I discuss with Dr. Edward Walker: The potential of plant-based extracts to significantly reduce hunger and cravings…05:27 The impact of antioxidants in blueberries and other berries on your body, and how they're processed differently than in the lab…07:30 The optimal timing of consuming antioxidants relative to exercise to maximize health benefits without impairing physical adaptation…12:32 Researching plant compounds that suppress appetite for weight loss application…16:13 How bitter compounds affect both appetite and blood glucose levels, with a focus on their roles in digestive processes…20:57 The identification and development of Amarasate®️ as an effective hunger suppressant, including the process of testing and standardization…26:22 The derivation of Amarasate from a specific variety of hops, highlighting its unique properties…34:47 The effects of miracle berry on taste perception and how it can transform the flavor profile of foods from bitter to sweet…37:28 A comparison between Amarasate and GLP-1 agonists like Ozempic, focusing on their benefits and side effects…39:21 The best timing and dosing strategies for Amarasate to maximize its hunger-suppressing properties…41:45 Results from clinical trials demonstrating Amarasate's efficacy in reducing food intake and managing hunger…44:37 The side effects associated with Amarasate, including its general tolerability and specific gastrointestinal impacts…49:12 The approach of using Akkermansia and other probiotics by Pendulum to modulate GLP-1 and its effects on blood glucose…51:04 Dr. Walker’s dietary habits and his preference for certain foods and beverages…53:26 Future research directions and planned studies on Amarasate, particularly its impact on weight loss and appetite control in specific population groups…54:43 Full Show Notes: https://bengreenfieldlife.com/hungerpodcast Additional Resources: Ben Greenfield Life Website: https://bengreenfieldlife.com/ Ben Greenfield Life Podcast: https://bengreenfieldlife.com/podcast/ Ben Greenfield Books: https://shopbengreenfieldlife.com/collections/books Instagram https://www.instagram.com/bengreenfieldfitness/ Facebook https://www.facebook.com/BGFitness X https://twitter.com/bengreenfield TikTok https://www.tiktok.com/@bengreenfield #BenGreenfield #ozempic #weightloss